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Spastic paraplegia four (SPG4; often called SPAST-HSP) is characterised by insidiously progressive bilateral lower-limb gait spasticity. Much more than 50% of afflicted men and women have some weak spot while in the legs and impaired vibration perception on the ankles.????? ??? ????? ???? ????.????? ???? ??? ??? ??? ???? ?????.A variant of ependymo

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